Masquelier writes: “To me it seems undesirable to cut the extract up into small parts. What would you want to do with them? We are not at all certain that each of the individual components could be stabilized. Let me remind you of the fact that one of my colleagues, Professor Bourzeix, with whom I’ve often worked together, and who works on oligomeres at the
INRA, the National Agronomical Research Institute in Narbonne, very patiently cut the extract up into ‘slices’ and lyophilized those, in order to protect them against oxidization and aging. He wanted to study their individual analytical and physiological behavior. This took a lot of time. It took at least two years to separate the components. And when he studied the first components to see how they had developed, analysis showed that they had changed completely. These components should only have resulted in a single chromatographic stain like any pure substance, but instead they produced two or three chromatographic stains. So when you try to isolate the constituents of OPC, albeit for a worthy cause, you are wasting your time.
FURTHER SEPARATION IMPAIRS EFFICACY Masquelier writes: “By themselves, these substances are not stable. For example: if you isolate the catechins from my extract, they once again become pure catechins, which are not soluble and unstable. You might isolate this dimer or that trimer and so on, but it would be very time-consuming and expensive. And you would end up with a substance which is less soluble and less stable. So this may be interesting from a scientific point of view, but it is disastrous from an industrial point of view.”
Masqueliers OPC observes the highest standard with regard to the treatment of the plant will the result be favorable. Everything depends on the quality of the solvents, the filtering, the centrifugation, the temperature, the freshness of the raw material used etc . . . Every kilo of biomass is analyzed before it is put out on the market, ensuring that the product meets pharmaceutical medicinal standards. Careful application of Masqueliers method renders a substance that contains a large amount of oligomeric proanthocyanidins. There are other ingredients as well, more specifically the water-soluble tannins (polymers) and catechins (monomers). Certainly, at the core of the range of extracted polyphenols are the oligomeric proanthocyanidins.Masquelier writes: “In other words, to explain what the plant gives us after the extraction has been applied, what we see is similar to what we find lying around a brick walls, with unused bricks lying all around it. You could say that catechins are like those bricks, they are building elements. By putting together bricks you build walls, and those walls together form a house. OPC is the house, the oligomeres, dimers and trimers are the walls. And the catechins are the bricks that are left over. But they no longer serve a purpose. We leave them where they are, because they are not toxic.” Buy Masqueliers pure OPC