• Warning Signs of Depression

• 9 Types of Depressive Disorder

• Is Someone You Love Depressed?

• The feel-good neurotransmitters, their primary functions and how to naturally enhance them

• Studies Suggest the Mind Makes, Breaks its Misery
• Hope for the chronically depressed
• The 23 best things to say to someone who Is Depressed
• The 99 worst things to say to someone who is depressed
• Scientists Have a Good Feeling About Exercise
• Physical Activity and Depression
• St. John's Wort and the treatment of Alcoholism
• Semen acts as an Anti-depressant?
• Tracing the Source of a Sense of Humor
• Brain part that appears to accentuate Negativity
• DNA Research links Depression to Family Ties
• Study Shows Genetic Link in Stress and Depression
• Active Mind's Linked to Brain Growth
• Depression raises heart attack risk

Personality Quizzes And
Other Miscellaneous Info

• Classifications of Pharmaceutical Antidepressant Drugs

• Non-research-grade SJW

• After treatment for depression, defensive lineman Dan Cody finds happiness in new position with Oklahoma

• What Is Premenstrual Dysphoric Disorder (PMDD)?

• Obsessive Compulsive Disorder (OCD) -A Self Quiz

• New JAMA study finds Lithium is best for preventing suicides

• New 20,638 person study links lithium to fewer suicides

• Out Of Darkness:
  Beach Boy Brian Wilson transcends decades of depression with release of album aptly titled 'Smile'

Frequently Asked Questions
About St. John's Wort

• How should I take St John's wort?
• Is it prudent to take St. John's Wort with antidepressants?
• Will St. John's Wort Help Menopausal Mood Swings?
• Can St. John's Wort Replace Prozac?
• Are There Withdrawal Symptoms For St. John's Wort?
• Are There Side Effects To Taking St. John's Wort?
• St. John's Wort Study Creates Consternation.
• Are There Interactions Between St. John's Wort And Tamoxifen?

Children's Corner

• An open-label pilot study of St. John's wort in juvenile depression.
• Antidepressant use by preschoolers rises dramatically
  Rates doubled in girls 5 and younger and rose 64% for boys in the same age group.
• Paxil Not For Kids, FDA Warns of Increased Suicide Risk
• N.Y. Charges Maker Hiding Paxil's Risks to Teenagers
• Anger and Children's Young Hearts
• Severely ill kids aren't more prone to depression in adulthood
• Emergent Suicidality in a Clinical Psychotherapy Trial for Adolescent Depression 
• Antidepressant Use for Kids Doubled Before FDA Warnings 
• Parental Control Affects Teen's Depression
• Childhood Conduct Problems May Predict Depression Among Young Adults

Celebrity Meltdown -
Famous, important people who have suffered depression

Art Buchwald  Sigmund Freud Greg Louganis Abraham Lincoln Shawn Colvin    Terry Bradshaw Jeff Reardon Stephen Fry Jordan Pete Doherty Kurt Cobain Bill Ward Roseanne Jean-Claude Van Damme Jackson Pollock Zack Greinke Senator Bob Antonioni Paul Dempsey Patrick Kennedy Lorraine Bracco Johnny Depp Kate Hudson Rick Springfield Uma Thurman Robbie Williams Jean Rhys Lindsay Lohan Amy Winehouse Zach Braff Britney Spears Richard Jeni Anna Nicole Smith Melanie Chisholm Owen Wilson Dorothy Hamill Elizabeth Wurtzel Richard Hammond Peter Mark Roget

William Styron  Marilyn Monroe Alanis Morissette Brooke Shields Dan Cody Pat Cash          Robbie Williams Robert Munsch Kerry Katona Adam Ant Jim Carrey Leonard Bernstein Beethoven Carrie Fisher Stuart Adamson Kelly Holmes Aleksandr Lukashenko Mary Chapin Steve Mason Vince Welnick Douglas Duncan Lily Allen Tom Petty Steven Bowditch Olivia Newton-John Emma Thompson Beyonce Knowles Mandy Moore Gary Lightbody Mutya Buena Lars von Trier J.K. Rowling Rick Parfitt Valerie Plame Patrick Dempsey Heath Ledger Mel Gibson Juliana Hatfield

Mike Wallace Ted Turner Lionel Aldridge Kieron Dyer Brian Wilson Carmen Electra Abraham Lincoln Phil Spector Steven Morrissey Diane Arbus Robert Blake Kurt Vonnegut Vincent van Gogh Tipper Gore Virginia Woolf Axl Rose Sebastian Diesler Carnie Wilson Margaret Trudeau Scott Harrison Eminem Ashley Judd James Dean Bradfield Darren Clark Andy Nicolson Alastair Campbell Yury Borzakovsky Orhan Pamuk Jessica Simpson Anne Hathaway Rosie O'Donnell Lena Headey Hillary Clinton Pete Wentz Neil Lennon Charmaine Dragun Delta Burke Heather Locklear

Other Nonpharmacologic 
Approaches to Depression

• From Reuters - First published in the February 2005 issue of Archives of General Psychiatry
  February 15, 2005
  DHEA eases midlife depression
• SAMe was shown to mitigate depressive symptoms in as little as 7 days
• New Clue to Bipolar Disorder
• Omega-3 Fatty Acids and Bipolar Disorder
• Fish Oils Ease Aggression/Depression
• HGH Improves Mood and Sleep Patterns
• New Study Indicates B-12 Levels Positively Affect Depression Treatments
•  Electroconvulsive ("Shock") therapy, depression, and the brain      New studies on ECT treatment for depression and its effects.
• Bursts of magnetic energy may ease severe depression and improve mood without inducing memory loss.
• Wondering if it's ok to take ST. John's Wort and 5-HTP?

NIH & FDA Warnings and Updates

• Brain circuit is linked to depression
• FDA Calls for Warnings on 10 Antidepressant Drugs:
  Celexa, Effexor, Lexapro, Luvox, Paxil, Prozac, Remeron, Serzone, Wellbutrin, Zoloft
• Bristol-Meyers Squibb to Halt Sales of Serzone in U.S.
• NIH Staff Must Report Payments
• Does SJW Have Side Effects?

• Mechanism of action of St John's wort in depression

• Taking the edge off: Why patients choose St. John's Wort

• Efficacy of St. John's Wort in major depression

• Summary of studies on Hypericum Vs Placebo

• Summary of 25 randomized clinical studies of Hypericum

• Studies comparing Hypericum Perforatum to synthetic anti depressants (St. John's Wort)

• What is the Hyperforin component of St. John's Wort?

• Efficiency and Safety of Hypericum in treatment of depression

• Pharmaceutical quality of hypericum extracts

• Clinical Criteria for review of St. John's Wort as antidepressive therapy

• St John's Wort for depression: a systematic review

• A Model for Examining Cost Savings Derived From Substituting St. John's Wort for Zoloft and Prozac

• Hypericum for depression. An update of the clinical evidence.

• The Influence of St. John's Wort on the Pharmacokinetics and Protein Binding of Imatinib Mesylate

• Additional Clinical Studies

Historical St. John's Wort Applications

The historical use of medical St. John's wort is well documented. Commencing 2400 years ago St. John's wort was used as a nerve tonic, a painkiller for arthritis, menstrual cramping, gastrointestinal problems (such as diarrhea, nausea . . . ) as well as ulcers.

The ancient Greeks and Romans used to treat many ailments, including sciatica and poisonous reptile bites as well as to ward against evil spirits, placing sprigs of the plant on statues of their Gods. In fact, the genus name Hypericum is from Greek and means "over an apparition" as the herb was once considered odiferous enough to cause evil spirits to depart.

In the first century St. John’s wort was referred to in Pliny the Elders famous book on natural history for its bracing quality in treating diarrhea and promoting urine flow and bladder troubles.

Dioscorides, a Roman army surgeon, recommended drinking St Johns wort in his medical text, “For it expels choleric excrements…” He also recommended rubbing it on burns. Paracelsus, a medical authority of the Renaissance also wrote of using St. John’s wort to treat wounds. He was also the first to mention using it for psychotic symptoms which he called “phatasmata”.

During medieval times, the Europeans used the plant to treat all forms of madness (They thought St. Johns wort had magical properties) as it blooms near the Summer Solstice. The Saltenitan drug list of the thirteenth century also referred to St. John’s wort as herba demonis fuga--an herb to chase away the devil.

Sixteenth century medical books refers to the plant as Fuga demonum, or devil’s scourge, a term that was repeated frequently in the literature of the next several hundred years.

The oil made from the flowers was listed in the first Pharmacopoeia Londinensis (1618). 1630 Angelo Sala stated that St. John’s wort treated illnesses of the imagination, melancholia, anxiety and disturbances of understanding. He wrote, “St. John’s wort cures these disorders as quick as lightening.” Gerard wrote that its use as a balm for wounds, burns, ulcers and bites was without equal (Gerard 1633).

There is even evidence that the American Indians used St. John's wort used it in the treatment of Tuberculosis and other breathing ailments.

Civil War soldiers collected St. John's wort to use on battle wounds. A prolific and hardy plant that threatened grazing land, a beetle was introduced into the Pacific Northwest in the early 1900's to keep St. John's wort under control.

19th century literature incorporated the use of hypericum to treat melancholia. 19th century British and American literature stressed the superficial use of the herb for the treatment of burns and wounds. A powerful antibacterial, St. John’s wort has been used through the centuries as an analgesic (pain reliever) to treat saddle sores and in poultices for certain lameness's in horses.

March 15, 2006
Roundtable: Prince Hamlet's depression and its neuroanatomical correlate

March 14, 2006
Mickey Mouse: A Cure For Depression?

March 13, 2006
Kelly Holmes on fighting depression

March 10, 2006
Injured athletes pushed into depression

March 9, 2006
Zack Greinke fighting depression

March 8, 2006
The 23 best things to say to someone who
Is Depressed

March 7, 2006
The 99 worst things to say to someone who is
depressed

March 6, 2006
SSRIs face next-generation
antidepressant replacement

March 3 , 2006
Kate Moss's off/on boyfriend, Pete Doherty treated for manic depression.

March 2 , 2006
Excess internet use can lead to depression in young: study

March 1 , 2006
Depression, heart disease often go
hand in hand

February 27, 2006
Researchers make depression gene breakthrough. Depression gene found

February 25, 2006
Childhood Depression May Raise Risk of Ecstasy Use,
Study Says it is linked to pre-existing depression

February 24, 2006
Women, declining estrogen and depression

February 23, 2006
Morrissey in depression shocker

February 22, 2006
Childhood depression; does it portend asthma and obesity as an adult?

February 20, 2006
Ex- Atomic Kitten Kerry Katona talks about beating depression

February 17, 2006
Disappearance linked to depression. Fears mount for missing woman.

February 15, 2006
Depression: Condition in Teenagers Can Be Life, Death
Glossary of Depression related Terms

February 14, 2006
Tips for Dealing with Valentine's Depression

February 11, 2006
Erasing memory helps depressed mice

February 9 , 2006
For some couples Valentines Day means coping
with depression together

February 8 , 2006
Jordan reveals treatment for depression

February 7 , 2006
SSRI's anti-depressant risk to infants

February 6 , 2006
Surfacing from depression

February 3 , 2006
Playing chess may help relief symptoms of depression

February 2 , 2006
Depression, Fatigue Fueled by Each Other

February 2 , 2006
Manic Depression Often Gets Misdiagnosed

February 1 , 2006
Study: Pregnancy No Cure For Depression

January 30, 2006
Guns, depression and rock 'n' roll: Documents show twilight of Spector's life

January 29, 2006
Thirty Minutes of Exercise Helps Relieve Major Depressive Symptoms

January 28, 2006
DHEA may reduce depression symptoms in HIV patients

January 27, 2006
Psychologist: A lifetime of abuse, depression led teen shooter to despair

Confession Tape: Part 2

January 26, 2006
Depression; Canine Loyalty

January 24, 2006
Is Jan. 24 — Tuesday — the most depressing day of the year?

January 23, 2006
Depression can be linked to violence

January 21, 2006
Robert Munsch driven by depression

January 17, 2006 Student suspended following depression treatment sues George Washington University

January 15, 2006
Poor diet link to rising cases of depression
Jo Revill, health editor,
The Observer

January 13, 2006
Scientists discover manic depression gene
Elizabeth Gosch

January 9, 2006
How Lincoln came to terms with depression
Book Review
How depression challenged a president and fueled his greatness

January 5, 2006
Romantic Breakups Change a Woman`s Brain
Grief sheds light on the connection between normal sadness, grief and depression

January 4, 2006
Williams Dismisses Depression Reports
Contact Music.com.UK

January 2, 2006
Income Level May Predict Response to Depression Treatment
Low-income people are less likely to respond to treatment 

December 29, 2005
1 in 10 US Teens Face Major Depression
Washington (Reuters)

December 27, 2005
Former Twins' Pitcher Jeff Reardon Arrested for Armed Robbery, Blames Depression Medication
(AP) Palm Beach Gardens, Fla.

December 22, 2005
Carmen Electra in Depression after deaths of brother and pet scorpion

December 20, 2005
Staving Off Holiday Stress and Depression
By Dr. Jon Gaudio

November 29, 2005
Chinese Government submits fast track application for St. John's Wort as new treatment for Avian Flu Virus

St John's Wort kills avian virus

November 25, 2005
Swimming with Dolphins Aids Depression

November 21, 2005
Senator John Hottinger reveals struggle with Depression
(WCCO) St. Paul 

November 21, 2005
Pat Cash, '87 Wimbledon champ, copes with suicidal tendencies

November 20, 2005
Scientists discover depression gene PDE4B
Revealing their findings in Science magazine, researchers have found a damaged PDE4B gene effects how the brain thinks.

November 19, 2005
Manic Depression Linked To Creativity
From New Scientis

November 9, 2005
Depression's Machismo Mask
You might call it melancholy on steroids

November 7, 2005
Shawn Colvin admits being on the verge of suicide
Says she went off depression medication and began using alcohol.

As reported in the British Medical Journal
2/11/2005 5:41 PM
St. John's Wort Matches Common Antidepressant (Paxil) At least as effective for moderate to severe depression as drug from Prozac family.As reported in Webb MD Health

Feburary 11, 2005
St. John's Wort Helpful In Severe Depression
New research shows the herbal supplement St. John's Wort to be as effective as one of the most popular prescription antidepressants for treating both moderate and severe depression.As reported in the BBC News

Friday, 11 February, 2005, 00:24 GMT
Herb As Good As Depression Drug
A German study has added weight to the argument that a herbal remedy is an effective treatment for depression.As reported in the Paris AFP

Feb 11, 2005
St. John's Wort as effective as widly used antidepressant.

From London - (German News)
March 7th 2005
St Johns Wort As Effective As Antidepressant Paroxetine AKA Seroxat With Fewer Side Effects

January 20, 2006
Stephen Fry
My depression and me -- Fry to talk of his misery

January 19, 2006
Program for pastors designed to help them understand depression