Any company wanting to introduce a medicine or dietary supplement on the market will have to at least prove that the substance is biologically available and in what amounts. This is an absolute requisite for the simple and obvious reason that substances that, though swallowed, do not spread throughout the body are useless. When Masquelier’s research really took shape, it could safely be said that the extract produced with his method consistently showed the most superior vitamin P action compared with that of all the other flavanol and bioflavonoid extracts. But in spite of all the positive results gathered during all the years of research and experience, it still wasn’t possible to claim that these results were directly attributed to OPC. It was never really sure if OPC could overstep the barriers of digestion in an unchanged or unaffected form. It could very well be that the effects on the vascular wall were realized by an unspecific fragment of the OPC molecule.
So when the French company Sanofi/Labaz decided to introduce Masquelier’s extract as a medicine to the market under the name of Endotelon, it still had to pass the great test. But, which of the available vegetal raw materials should one choose to perform the test with? Masquelier remembers, “I needed to check the bio-availability of OPC grape seed extract. In order to verify whether it is bio-available, I marked it with 14-carbon, rendering it radioactive. So, we had to grow the plant we wanted to obtain the OPC from in an artificial atmosphere with a high radioactive CO2 content. Through photosynthesis, all the elements in the plant which contain carbon exchange their ordinary carbon for radioactive carbon. I used vines to obtain radioactive OPC by keeping the vines in the phytotron for 45 days. I was then able to experiment with the bioavailability by administering the radioactive OPC to laboratory animals.” Buy Authentic Masqueliers OPC. Buy three, get one free. Lowest price in the world.