Regenerate New Mitochondria with PQQ

Support peak performance with “the other CoQ10.”

As we age, disease, oxidation and oxidative stress extinguishes our mitochondria. PQQ, a component of every living cell on earth, helps restore mitochondrial DNA.

Mitochondrial malfunction has been conclusively linked to practically every killer disease of the elderly including; diabetes, Parkinson’s disease, Alzheimer’s, heart disease, heart failure . . . the list goes on. Geriatric brain cells have much more mitochondrial damage then the brains of younger people. At age 70 mitochondrial death runs approximately 50% depriving our most energy intensive organ. For this reason, researchers have concluded that mitochondria do directly influence brain life longevity.


PQQ addresses our brain’s neurotransmission system by protecting neurons in the NMDA receptor site. NMDA is a glutamate receptor and ion channel protein found in nerve cells. Brain cells can be overstimulated by seizures and neuro-degenerative diseases. PQQ protects the brain from neurotoxins like mercury, lead, and cadmium. In another study released this year Pyrroloquinoline quinone (PQQ), guarded against 6-OHDA-induced neuro-toxicity, which causes cell death and DNA fragmentation. By contract vitamin C and vitamin E had no neuroprotective effect. PQQ also effectively scavenges superoxide. Superoxide radicals are a byproduct of normal oxygen metabolism that causes cell mitochondria damage. When this happens, cells cannot convert food to energy and they die. Then disease takes over.

Both Alzheimer’s and Parkinson’s disease are triggered by an accumulation of abnormal proteins that initiate a cascade of harmful oxidation that results in brain cell death. Studies have shown PQQ can inhibit the development of alpha-synuclein a protein associated with Parkinson’s as well as the oxidizing ravages of the amyloid-beta protein linked with Alzheimer’s.


Pyrroloquinoline quinone (PQQ) has been shown to improve memory by reversing cognitive impairment caused by chronic oxidative stress. It also addresses reactive nitrogen species (a leading cause of strokes). PQQ suppresses reactive nitrogen. It also supports the massive post stroke blood reinfusion called ischemia reperfusion.

PQQ is an essential growth factor for cellular youth. PQQ is everywhere. Every animal and plant species has it. It has even been found in interstellar stardust. Because the body cannot produce its own PQQ it must be taken in from an outside source. Nutrients that the body cannot produce are called essential nutrients.

Repeated findings show PQQ’s consistent mitochondrial enhancement renders it a powerful role in growth and development.

When test animals were deprived of pyrroloquinoline quinone they evidenced stunted growth, immunity issues, impaired reproductive capability, and their young experienced a lower survival rate. When lab specimens were supplemented with PQQ their mitochondria increased leading to restored organ function.

Mighty mitochondrial defense

Our mitochondria are fragile organelles. To be sure, basic life is constantly bombarding our mitochondria with free radicals. One of the things that distinguishes PQQ from other antioxidants is its extraordinary stability. Free radicals like superoxide and hydroxyl radicals are unstable molecules in search of electrons for stability. PQQ is thirty (30) to five thousand times more efficient in sustaining stable mitochondrial production. This allows it to execute millions of electron transfers without breaking down. The net result is increased energy.



  • Idebenone and PQQ collaboration
  • While Idebenone is an excellent antioxidant found to optimize mitochondrial function, PQQ synergizes mitochondrial repair and reproduction. Many practitioners recommend five hundred milligrams of Idebenone concomitant with twenty milligrams of PQQ for older people with heart and cognitive deterioration.


8 ways Pyrrologuinoline quinone supports health

    1. Heart/Circulatory Health

PQQ has acquired a persistent reputation as being heart protective. PQQ can help reduce cholesterol and triglyceride levels which puts it on the right side of heart health/stroke equation. Heart cells are very high demand energy consumers. Optimal mitochondrial function is fundamental extended heart health. 


PQQ neutralizes inflammation. The Journal of Nutritional Biochemistry published a study demonstrating how PQQ supplementation significantly decreased inflammation markers after only three days of supplementation.  A study in the journal Inflammation, researchers described the benefits of PQQ in degenerative joint disease in rodents. The joint cartilage was analyzed and found to have significantly reduced inflammation when quenched with PQQ administration.

    1. Liver Health

There are currently 32 PQQ/liver studies abstracted on demonstrating PQQ’s liver protective effects especially from non-alcoholic (sugar based) fatty liver disease. Feel free to click on the above link to view them.

    1. Male/Female Sexual Energy

Animal studies demonstrated that problems with fertility and reproduction due to low PQQ were improved when PQQ was added back into the diet.

Studies on human skin and connective tissue cultures found that low PQQ leads to a loss of elasticity and tissue health. Gut diverticulitis, a leading cause of hemorrhage was also improved by PQQ.  A positive effect on connective tissue health was noted during PQQ supplementation. Idebenone is an excellent co supplement with PQQ for maximum skin protection from UVA/UVB radiation.

6. Thyroid Health

Pyrroloquinoline quinone (PQQ) has shown the ability to be of therapeutic use for hyperthyroidism. Administration of PQQ (5 mg kg−1 for 6 days) ameliorated negative conditions, indicating the potential of PQQ in the amelioration of hyperthyroidism and associated problems.


7. Weight Control


Elevated PQQ levels triggers the extra energy you need to get up and start burning calories. A University of California Davis found that taking a PQQ supplement increased metabolism in rats. 




The retina has the highest metabolic need for mitochondrial density in the body. The eyes also display progressive age-related inflammation and marked cell loss. PQQ is a key element in mitochondrial respiration. In a recent study the application of potassium pyrroloquinoline quinone (PQQ) demonstrated a preventive effect against the HC-induced cataract formation. PQQ also prevented the decline of GSH in the lens caused by HC. The decline of GSH in liver 24 hours subsequent to HC administration was prevented by PQQ. Hence, data indicates that PQQ can have a preventive effect on cataracts in the lens.

100 Research Grade PQQ Caps


Pyrroloquinoline Quinone

The ultimate cellular rejuvenator

20 mg, 100 vegetarian capsules Retail Price: $99.00

Our Price: $39.95  SAVE 50%





Or, buy three and get one free for an additional 25% SAVINGS Your price 119.85   


Supplement Facts

Serving Size 1 vegetarian capsule
Amount Per Serving
PQQ (Pyrroloquinoline quinone) disodium salt

20 mg

Other ingredients: rice bran, rice flour, vegetable cellulose (capsule), silica.


Dosage and Use
  • Take one (1) capsule daily with or without food, or as recommended by a healthcare practitioner.

  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1.800.497.3742

Each capsule contains 20 milligrams. Studies have shown that an average daily dose of 20 milligrams of PQQ per day, five days per week, is sufficient to maintain optimal mitochondrial health. Taking more than that will not be of greater benefit.

Dosage: 20 mgs per day 5 days per week.